龔佳男，1986年生，籍貫河南，細胞生物學家，醫學實驗動物研究所研究員，博士生導師。2004年考入西北農林科技大學生物技術專業，2008年獲得學士學位。2008年至2013年在北京協和醫學院基礎學院進行碩博連讀培養，攻讀博士學位，從事microRNAs在正常造血和腫瘤中的功能機制研究。2013年底進入澳大利亞伊麗莎白霍爾醫學研究所/墨爾本大學生物醫學系進行博士后研究工作，主要研究細胞凋亡與腫瘤。2021年聘任為研究員。

主要研究方向包括構建消化道腫瘤疾病模型，利用體外和體內CRISPR文庫篩選研究腫瘤癌變機理并尋找治療新靶點，研究腸道微生態與腫瘤發生發展以及治療相關機制研究。

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1. Ming?Jie Luo#, Michelle Palmieri#, Chris D Riffkin, Anuratha Sakthianandeswaren, Tirta Mario Djajawi, Yumiko Hirokawa, Victoria Shuttleworth, David H Segal, Christine A White, Duong Nhu, Guillaume Lessene, Margaret Lee, Peter Gibbs, David CS Huang*, Oliver M Sieber* and Jia-Nan Gong*. Define the susceptibility of colorectal cancers to BH3 mimetic compounds. Cell Death Disease. 2020 Sep 10;11(9):735. (IF=6.304）

2. Piers Blombery#, Mary Ann Anderson#, Jia-nan Gong#, Rachel Thijssen#, Richard W.Birkinshaw#, Ella Thompson, Charis E. Teh, Tamia Nguyen, Zhen Xu, Christoffer Flensburg, Thomas E. Lew, Ian J. Majewski, Daniel H.D. Gray, David A. Westerman, Constantine S. Tam, John F. Seymour, Peter E. Czabotar, David C.S. Huang, Andrew W. Roberts. Acquisition of the recurrent Gly101Val mutation in BCL2 confers resistance to venetoclax in patients with progressive chronic lymphocytic leukemia. Cancer Discovery. 2019 Mar;9(3):342-353. (IF=29.497）

3. Jia-nan Gong#, Tiffany Khong, David Segal, Yuan Yao, Chris D. Riffkin, Jean-Marc Garnier, Seong Lin Khaw, Guillaume Lessene, Andrew Spencer, Marco J. Herold, Andrew W. Roberts, David C. S. Huang. Hierarchy for targeting prosurvival BCL2 family proteins in multiple myeloma: pivotal role of MCL1. Blood. 2016 Oct 6;128(14):1834-1844. (IF=13.164）

4. Gong JN#, Yu J#, Lin HS#, Zhang XH, Yin XL, Xiao Z, Wang F, Wang XS, Su R, Shen C, Zhao HL, Ma YN, Zhang JW. The role, mechanism and potentially therapeutic application of microRNA-29 family in acute myeloid leukemia. Cell Death Differ. 2014 Jan;21(1):100-12. (IF=8.184）

5. Jia-nan Gong#, Jianxiong Li#, Yi Wang#, Changzheng Liu#, Hongyan Jia, Chongliang Jiang, Yuxuan Wang, Min Luo, Hongmei Zhao, Lei Dong, Fang Wang, Junwu Zhang*, Jia Yu*. Characterization of microRNA-29 family expression and investigation of their mechanistic and therapeutic roles in gastric cancer. Carcinogenesis. 2014 Feb; 35(2):497-506. (IF=5.334)

6.  Xiao-Shuang Wang#, Jia-Nan Gong#, Jia Yu, Fang Wang, Xin-Hua Zhang, Xiao-Lin Yin, Zhen-Qing Tan, Zi-Mian Luo, Gui-Hua Yang, Chao Shen, Jun-Wu Zhang*. MicroRNA-29a and microRNA-142-3p are regulators of myeloid differentiation and acute myeloid leukemia. Blood. 2012 119:4992 -5004. （IF=9.06, C100, ESI）