張曉輝，1988年生，籍貫河南周口，系統醫學研究院研究員，博士生導師。2008年考入河南科技大學大學生物科學專業，2012年獲得學士學位。2012年在昆明理工大學大學生物化學與分子生物學專業攻讀碩士學位。2016年在華東師范大學生物化學與分子生物學專業攻讀博士學位，從事基因編輯技術開發與優化研究。2020年博士畢業后受聘華東師范大學生命科學學院副研究員，從事基因編輯工具的開發、優化以及在疾病動物模型和基因治療方面的應用。

擬從酶定向進化、蛋白理性設計和DNA損傷修復機制等角度入手探索現有基因編輯工具技術瓶頸的解決方案，并嘗試在體基因治療可行性，為臨床重大疾病基因治療提供可行性方案。

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4. Lei Yang#, Xiaohui Zhang#, Liren Wang#, Shuming Yin#, Biyun Zhu, Ling Xie, Qiuhui Duan, Huiqiong Hu,Rui Zheng, Yu Wei, Liangyue Peng, Honghui Han,Jiqin Zhang, Wenjuan Qiu, Hongquan Geng,Stefan Siwko, Xueli Zhang, Mingyao Liu, Dali Li*. Increasing targeting scope of adenosine base editors in mouse and rat embryos through fusion of TadA deaminase with Cas9 variants. Protein & Cell 9, 814-819 (2018). (Cover story, Highlight by Protein & Cell ). (IF=7.575)

5. Xiaohui Zhang#, Liren Wang#, Mingyao Liu* and Dali Li*. CRISPR/Cas9 system: a powerful technology for in vivo and ex vivo gene therapy. Sci. China Life Sci. 60(5):468-475 (2017) . (IF=3.085)

6. Zhang, X.-H.#, Tee, L.Y., Wang, X.-G., Huang, Q.-S. & Yang, S.-H*.. Off-target effects in CRISPR/Cas9-mediated genome engineering. Molecular Therapy-Nucleic Acids 4, e264 (2015). (IF=5.048, ESI 1%)