許琪，2004年畢業于中國協和醫科大學，獲博士學位。現任中國醫學科學院基礎醫學研究所/北京協和醫學院基礎學院副所院長，中國醫學科學院神經科學中心常務副主任（主持工作），中國醫學科學院長聘教授，國家級重大人才項目入選者，國家杰出青年基金獲得者。長期從事抑郁癥、精神分裂癥、難治性癲癇、癡呆等重性腦疾病的發病機制與診療靶標研究。在Nature、Neuron、American Journal of Psychiatry、Journal of Experimental Medicine等期刊發表通訊作者論文80余篇，成果被Nature、Nature Reviews Drug Discovery等廣泛報道

研究方向為重性腦疾病的發病機制和診斷治療靶標研究，主要研究內容包括：重性腦疾病的遺傳學與表觀遺傳學研究；重性腦疾病的致病機制研究；重性腦疾病的治療靶點和新藥研發；重性腦疾病的干細胞與再生醫學研究。

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2. Enhui He#, You Zhou#, Jinping Luo, Shihong Xu, Kui Zhang, Yilin Song, Mixia Wang, Shengwei Xu, Yuchuan Dai, Gucheng Yang, Jingyu Xie, Zhaojie Xu, Wanwan Zhu, Yu Deng, Qi Xu*, Xinxia Cai*. Sensitive detection of electrophysiology and dopamine vesicular exocytosis of hESC-derived dopaminergic neurons using multifunctional microelectrode array. Biosens Bioelectron. 2022. 209:114263. (IF=12.54)

3. Shu Liu#, Jianbo Xiu#, Caiyun Zhu#, Kexin Meng#, Chen Li, Rongrong Han, Tingfu Du, Lanlan Li, Lingdan Xu, Renjie Liu, Wanwan Zhu, Yan Shen, Qi Xu*. Fat mass and obesity-associated protein regulates RNA methylation associated with depression-like behavior in mice. Nat Commun. 2021. 26;12(1):6937. (IF=14.91)

4. Qiu-Wen Wang#, Si-Yao Lu#, Yao-Nan Liu#, Yun Chen, Hui Wei, Wei Shen, Yan-Fen Chen, Chong-Lei Fu, Ying-Han Wang, Anbang Dai, Xuan Huang, Fred H Gage, Qi Xu*, Jun Yao*. Synaptotagmin-7 deficiency induces mania-like behavioral abnormalities through attenuating GluN2B activity. Proc Natl Acad Sci USA. 2020. 117(49):31438-31447. (IF=11.20)

5. Lige Leng#, Kai Zhuang#, Zeyue Liu#, Changquan Huang, Yuehong Gao, Guimiao Chen, Hui Lin, Yu Hu, Di Wu, Meng Shi, Wenting Xie, Hao Sun, Zhicheng Shao, Huifang Li, Kunkun Zhang, Wei Mo, Timothy Y Huang, Maoqiang Xue, Zengqiang Yuan, Xia Zhang, Guojun Bu, Huaxi Xu, Qi Xu*, Jie Zhang*. Menin Deficiency Leads to Depressive-like Behaviors in Mice by Modulating Astrocyte-Mediated Neuroinflammation. Neuron. 2018. 100(3):551-563. (IF=14.43)

6. Longze Sha#, Xueqin Wang#, Jing Li, Xinze Shi, Liwen Wu, Yan Shen, Qi Xu*. Pharmacologic inhibition of Hsp90 to prevent GLT-1 degradation as an effective therapy for epilepsy. J Exp Med. 2017. 214(2):547-563. (IF=11.99)

7. Na Cai#, Tim B. Bigdeli#, Warren Kretzschmar#, Yihan Li #, Qi Xu*, Jun Wang*, Kenneth S. Kendler* & Jonathan Flint*. Sparse whole-genome sequencing identifies two loci for major depressive disorder. Nature. 2015. 523(7562):588-91. (IF=37.54, F1000)

8. Hui Wei#, Yanbo Yuan#, Sha Liu, Cheng Wang, Fude Yang, Zheng Lu, Chuanyue Wang, Hong Deng, Jinping Zhao, Yan Shen, Chenyu Zhang*, Xin Yu*, Qi Xu*. Detection of circulating miRNA levels in schizophrenia. Am J Psychiatry. 2015. 172(11):1141-7. (IF=13.50)

9. Yongyong Shi*#, Zhiqiang Li#, Qi Xu#,Ti Wang, Tao Li, Jiawei Shen, Fengyu Zhang, Jianhua Chen, Guoquan Zhou, Weidong Ji, Baojie Li, Yifeng Xu, Dengtang Liu, Peng Wang, Ping Yang, Benxiu Liu, Wensheng Sun, Chunling Wan, Shengying Qin, Guang He, Stacy Steinberg, Sven Cichon, Thomas Werge, Engilbert Sigurdsson, Sarah Tosato, Aarno Palotie, Markus M N?then, Marcella Rietschel, Roel A Ophoff, David A Collier, Dan Rujescu, David St Clair, Hreinn Stefansson, Kari Stefansson, Jue Ji, Qingzhong Wang, Wenjin Li, Linqing Zheng, Hairong Zhang, Guoyin Feng,Lin He*. Common variants on 8p12 and 1q24.2 confer risk of schizophrenia. Nat Genet. 2011. 43(12):1224-7. (IF=35.53, C100)

10. Weirui Guo#, Yanbo Chen#, Xiaohong Zhou#, Amar Kar, Payal Ray, Xiaoping Chen, Elizabeth J Rao, Mengxue Yang, Haihong Ye, Li Zhu, Jianghong Liu, Meng Xu, Yanlian Yang, Chen Wang, David Zhang, Eileen H Bigio, Marsel Mesulam, Yan Shen, Qi Xu*, Kazuo Fushimi, Jane Y Wu*. An ALS-associated mutation affecting TDP-43 enhances protein aggregation, fibril formation and neurotoxicity. Nat Struct Mol Biol. 2011. 18(7):822-30. (IF=12.71, C100)